Alzheimer’s Brain

This is a brain set to represent Alzheimer’s disease. This is a relatively common and devastating disease that affects a person’s memory.

In the brain there are plaques and tangles that are indicative of Alzheimer’s. These two abnormal structures are thought to contribute to killing neurons.

Plaques are made up of beta amyloid protein that builds up between neurons.

Neurofibrillary tangles are made up of tau protein that accumulated inside the neuron.

It is generally thought that the plaques and tangles block communication and promote death of neurons. This leads to loss of memory characteristic of Alzheimer’s disease.

This brain is an experiment with modeling past. I cut out a foam brain, added a layer of past and textured it. That was followed by adding paste to give the neurons a 3D structure. The color theme is purple, the “official” color for Alzheimer’s disease. The background of the brain is dark purple. The light purple neurons are uninjured, normal neurons. The darker purple neurons that are smaller with a pink glow are the dying neurons of the disease. There are strings on the neurons to represent tau protein and neurofibrillary tangles. The light whitish strings structures between the neurons represent beta-amyloid plaques, a hallmark of Alzheimer’s.

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